p-wave dispersion in patients with major thalassemia

نویسندگان

a ghadiri anari assistant professor of endocrinology ,shahid sadoughi university of medical sciences and health services ,yazd, iran

r ghiliyan r department of internal medicine, shahid sadoughi university of medical sciences and health services, yazd, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences)

g rezaeian cardiology department, shiraz university of medical sciences, shiraz, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید صدوقی یزد (shahid sadooghi university of medical sciences)

چکیده

abstract background prolonged p-wave duration and p-wave dispersion indicate interatrial conduction disturbance and early predict arrhythmia especially atrial fibrillation. iron deposition in the atrial tissue might prolonged the atrial conduction time, and this study evaluated the p-wave prolongation and increased p-wave dispersion in these patients. materials and methods fifty patients with major thalassemia and fifty healthy controls were studied, which age and sex matched between cases and controls. all patients and the controls were examined and had an ecg. the p-wave dispersion defined as the difference between the maximum and minimum p-wave duration. p-wave dispersion was compared between two groups. student^,s t-test and pearson^,s correlation were used as needed. results there was a significant difference between the p-wave dispersion of the 2 groups (p=0.019). maximum p-wave duration and p-wave dispersion in patients had strong correlation with age (disease duration). p-wave duration and p-wave dispersion had no correlation with regularity or irregularity of desferal use. conclusion maximum p-wave duration and p-wave dispersion were seen in older cases, which significantly get prolonged. this could show that the myocardial involvement and dysfunction was probably more in the older patients.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

P-wave Dispersion in Patients with Major Thalassemia

Abstract Background Prolonged P-wave duration and P-wave dispersion indicate interatrial conduction disturbance and early predict arrhythmia especially atrial fibrillation. Iron deposition in the atrial tissue might prolonged the atrial conduction time, and this study evaluated the P-wave prolongation and increased P-Wave dispersion in these patients. Materials and Methods Fifty patients w...

متن کامل

QT dispersion and P wave dispersion in patients with fibromyalgia.

OBJECTIVE Fibromyalgia (FM) is a chronic disease characterized by widespread pain. Somatic complaints associated with the cardiovascular system, such as chest pain and palpitations, are frequently seen in FM patients. P and QT dispersions are simple and inexpensive measurements reflecting the regional heterogeneity of atrial and ventricular repolarization, respectively. QT dispersion can cause ...

متن کامل

Cardiac Iron Load and Novel P-Wave Measurements in Patients with Thalassemia Major

The deleterious effects of cardiac iron load on the ventricular repolarization were demonstrated in beta-thalassemia major (βTM), but little is known about the P wave measurements, an independent risk factor for development of atrial fibrillation (AF). We aimed to examine relationship between P-wave parameters and iron loading using cardiac T2* Magnetic Resonance Imaging (MRI) in asymptomatic β...

متن کامل

Endocrine Dysfunctions in Iron Overload in Patients with Major Thalassemia

Abstract Background The aim of the present study was to determine the endocrine dysfunction in patients with major thalassemia, who receive hyper transfusion. Materials and Methods This cross sectional study was performed during one year, which included 65 major thalassemia patients (31 females and 34 males), aged between 14 month to 27 years old (median 10,3). Growth assessment was measur...

متن کامل

P-wave and QT dispersion in patients with conversion disorder

OBJECTIVE The aim of this study was to investigate QT dispersion (QTd), which is the noninvasive marker of ventricular arrhythmia and sudden cardiac death, and P-wave dispersion, which is the noninvasive marker of atrial arrhythmia, in patients with conversion disorder (CD). PATIENTS AND METHODS A total of 60 patients with no known organic disease who were admitted to outpatient emergency cli...

متن کامل

Quality of life in patients with thalassemia major

Background With modern medical management, thalassemia major is now extending into adulthood and it is expected to have a negative impact on the quality of life (QOL) of the patients. The aim of this study was to evaluate quality of life in patients with thalassemia major. Materials and Methods This is an analytic case control study. Two hundred and fifty patients and 51 participants a...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pediatric hematology and oncology

جلد ۲، شماره ۲، صفحات ۶۷-۷۱

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023